RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Grem2
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Immunohistochemistry; Immunofluorescence; qRT-PCR etc.
Target
NA
Pathway
NA
PubMed ID
Title
Gremlin2 Activates Fibroblasts to Promote Pulmonary Fibrosis Through the Bone Morphogenic Protein Pathway
Year
2021
Function
"Compared with the commonly used fibrosis indexes involving collagen1 (Col1) and fibronectin (FN), we found that the Gremlin2 expression level in the fibrosis model mice group increased more significantly, and was even more sensitive and indicative than the international indexes."